Thank you for the OSMO Patches they arrived Friday 18th February just five days after I placed an order! OSMO Patches have the Wow factor. I used two patches at a time, one on the popiteal cyst and one on the calf. After four days the popiteal cyst was so much better. I have just ordered another pack of ten. I was amazed after I took the first patches of my leg after 8 hours. My Physio was impressed! I still have some swelling in the knee so fingers cross the next lot of OSMO Patches will do the trick.